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The associations of smoking and alcohol drinking with total mortality are influenced by health and lifestyle confounders (education, body mass index, hypertension, diabetes, physical activity, and fruit and vegetable consumption), both between and within countries. We examined the extent to which effects of both these lifestyle factors on total mortality could be explained by known health behavior correlates. We used data on over 1.4 million Finnish men and women aged 25-84 years from 1984 to 1998 for analyses, with follow-up until 31 December 2005. Each subject was monitored in three categories based on annual self-reports of alcohol consumption and smoking during the past year: abstainers, light drinkers [1-10 g/day ethanol (E), former drinkers], and heavy
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Economics & Finance. It is the faculty of Science, Mathematics, Engineering, and Applied Sciences, in general. A department of a university is a specialized. of Economics & Finance.Â .
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Applied Economics (PDF): “One of the most striking features of the above episode is that the increase in economic.A bipartite, linker-independent motif for DNA recognition in type-B DNA topoisomerase.
Type II topoisomerases make transient double-strand breaks in DNA to relax positively supercoiled DNA. The architecture of DNA binding and catalytic machinery of type II topoisomerases is conserved from archaeal to human. Type II topoisomerases in Escherichia coli have a 140 kD dimer that contains both an ATPase and an enzyme that can cleave DNA. The dimer is composed of two 100 kD subunits that each contain three domains (I, II, and III). The enzyme-subunit interface is highly conserved in the three domains of the E. coli enzyme. Here we show that a corresponding interface in the human enzyme also contains a conserved tripartite domain