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Category:2005 video games
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Category:THQ gamesStudy on the relationship between serum angiotensin-converting enzyme and arterial pressure in essential hypertension.
The relationship between blood pressure and serum angiotensin-converting enzyme (ACE) concentration was studied in 40 patients with essential hypertension, who were treated with enalapril. Following six weeks of treatment, these patients were divided into two groups: in 15 patients, blood pressure was less than 140/90 mm Hg, whereas in the remaining 25 it was 140-170/90-115 mm Hg. Serum ACE concentration was low in all the patients; the values of the lower and higher blood pressure groups did not differ. This finding suggests that differences in serum ACE concentrations between patients with and without essential hypertension are caused mainly by alterations in the renin-angiotensin system and that they do not play a definite part in the pathogenesis of essential hypertension.Application Information
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Declaration of Interest:
Idenix Biopharmaceuticals, Inc. is developing targeted therapies for the treatment of neurodegenerative and infectious diseases, including Parkinson’s disease, Alzheimer’s disease and AIDS, HIV, and Ebola.
Idenix has identified an Ebola glycoprotein which specifically binds to the brain neuron cell surface and is internalized through the binding to the fluid phase of brain blood vessels. Idenix has developed a proprietary technology to make the Ebola glycoprotein into an antibody-mediated therapeutic, which will pass the blood-brain barrier and bind to the Ebola glycoprotein on the surface of brain neurons. If the antibody is internalized through binding to the fluid phase of brain blood vessels, then the Ebola glycoprotein on the surface of brain neurons is specifically targeted, and the cell (neuron) is killed. This provides a complete cell kill with far fewer side effects than traditional broad-spectrum (non-targeted) antibiotics used to treat Ebola. Idenix has shown in vitro that the Ebola glycoprotein antibody-mediated targeted therapeutic is superior in efficacy to broad-spectrum antibiotics used to treat Ebola, and has now gone on to its first in vivo/rod